Human Growth Hormone (HGH): Functions, Benefits, and Risks
The hype around the role of growth hormone (GR) in the fight against aging erupted in the 1990-ies, thanks to the publication of Daniel Rudman, a researcher at the Medical College of Wisconsin. Human Growth Hormone
He published the results of the study, in the presence of a control placebo group, in which 21 men aged 61 to 81 years took part. Among all the positive effects of growth hormone, it revealed the following: an increase in muscle mass, a decrease in adipose tissue, improved bone health, improved cholesterol and a more sensitive perception of insulin.
Numerous such studies have come to the same results. In online search engines of the National Medical Library, 48 000 articles are published on the request of the “growth hormone”. It should be noted that it is very unlikely that growth hormone therapy will help gain muscle mass and get rid of fat without a diet and a set of exercises.
Human Growth Hormone (HGH)
GR has a positive effect on the work of the cardiovascular system, lipid metabolism and blood pressure. In patients who have been treated for GP for 7 years, a decrease in insulin susceptibility to insulin, which occurs during aging, reversed. Human Growth Hormone
Injections of GP were previously used to treat children who were diagnosed with its deficiency. But a lack of growth hormone in adults, which is now called growth hormone deficiency in adults (GHDI), is recognized as a separate syndrome, the treatment of which GH was approved by the Commission for Drugs and Nutrient Control.
Although the positive effects of GH therapy are obvious, some dark sides should be noted. This is quite expensive treatment, from 2 000 to 8 000 dollars per year, depending on the required dose and it is not always covered by insurance. Treatment requires daily injections and their benefits for healthy people are quite contradictory.
In 2002, the National Institutes of Health sponsored a study that observed 121 people after a course of GR injecting or without synthetic hormone replacement therapy in 1992 and 1998.
The results of the Rudman report on muscle gain and fat loss were confirmed, but the following side effects were also revealed: 24% of men developed glucose resistance or diabetes, 32% had carol syndrome, 41% had joint aches. 39% of women have developed dropsy. The authors of the study concluded that “due to the frequent occurrence of side effects (especially diabetes and glucose resistance), the use of GH therapy to adults should be limited to the framework of studies conducted.”
Human Growth Hormone (HGH)
At the moment, there is a debate about the likelihood of increasing the risk of cancer after undergoing GR therapy. But Shim and Koen of the California Uniersitia in Los Angeles said: “The risk of cancer is not increasing much than usual among the population,” in addition to which other studies also did not confirm the increase in cancer rates of rectal or prostate cancer.
Since the therapy of GR in the fight against aging is used not so long ago, we must not forget about the possible side effects. It is very important to understand that long-term studies on the safety of injections of GR by healthy adults are still ahead. Fortunately, it is in our power to change the usual way of life so as to achieve results in the injections without resorting to the injections themselves. Human Growth Hormone
Sugar and high-glycemia carbohydrates reduce the production of GH in the pituitary gland, and a protein diet, on the contrary, contributes to its production. Adhering to a low-sugar diet and low glycemic load, you will increase the level of GG in the body.
Deep sleep and anaerobic exercise are the two main factors in stimulating the production of GR in healthy people. Adults who continue to play sports throughout their lives retain muscle mass and higher levels of GH.
The use of certain amino acids, such as arginine, ornitine, glycine, and glutamine, stimulates the pituitary g released more. Supplements with different amounts of these amino acids are wide available, they are also called secretion stimulants, as they encourage the pituitary gland to release the pleunier from reserves.
Supplements containing DEA are an inexpensive way to increase the level of GH.
For most people who would like to feel the effectiveness of the anti-aging effect of growth hormone, it is recommended to adhere to the above recommendations. Until the results of further studies are known, we advise you to leave injections of the GHI only to adults with a diagnosis of DGRV, based on the conclusion of an experienced doctor.
Before taking any of the listed measures, check the level of IGF-1 (insulin-like growth factor -1) in the blood. IGF-1 gives more accurate results than the level of GH, as IGF-1 gives an average value of the level of GR, which constantly fluctuates in the bloodstream. Based on your age and gender, your doctor will be able to determine the optimal level for you.
Our rudimentary organs
As soon as we invent technologies that will support nutrients and other substances in the blood at the right level, we will not need organs that are responsible for the production of chemicals, hormones and enzymes. In the human body, versions 2.0, hormones and related substances will be delivered with nanorobots, and the biological feedback system will monitor the production of substances and maintain the necessary balance between them.
In the end, it will be possible to avoid the presence of most of our biological organs. This re-screen process cannot be completed at one time. Each body and every idea requires its own development, a semi-finished product and stages of implementation. However, we are aimed at fundamental and radical changes of the absolutely imperfect, unreliable and functional version of the human body 1.0.
гормоны юности, гормоны старения
Melatonin
According to some data, at least 50% of all Americans aged 65 suffer from sleep disorders, although sleep plays an important role in the health of the body. Prolonged sleep disorders lead to depression and suppression of the immune system.
Melatonin is a light-sensitive hormone that is rhythmically formed in the human epiphysis located deep in the brain. The daily rhythm of a person is controlled by internal biological clocks. During the day, the melatonin level decreases and increases in the evening before going to bed.
The melatonin level reaches its peak by midnight, lasts for a while and then begins to decline. The production of melatonin depends on the daily cycle. The duration of melatonin production depends on the duration of darkness, so it turns out that the largest amount of melatonin is produced in winter than summer.
The peak of melatonin production is reached by the age of seven. Then it drops sharply to adolescence. By the age of 45, the epiphysis begins to contract and loses the melatonite-producing cells.
The hormone begins to develop chaotically. By the age of 60, only 50% of the amount of melatonin that was produced at the time of your twenties is formed, which explains why many older people experience sleep problems. Recent studies of double anonymity with the control group – placebo have proven that melatonin supplements help to solve sleep problems for people over 55.
Melatonin is a strong antioxidant and is highly valued when dealing with certain types of cancer, such as breast cancer.
With an insufficient level of melatonin, the following vicious circle occurs:
1. The body loses the ability to produce more melatonin and begins to grow faster.
2. In the process of aging, the production of melatonin is further reduced
3. Reducing the level of melatonin serves as a signal for other glands and organ systems, which is the time for a well-deserved rest. In women, the ovaries cease to function, estrogen levels drop, menopausal syndrome occurs. In men, despite the fact that sperm continues to be produced, testosterone decreases.
4. In both sexes, the immune system weakens, exposing us to various diseases, ranging from infections to cancer and autoimmune diseases (a state of the immune system revolt against the body’s own tissues).
5. Then there are violations in the work of organ systems, which increases the speed of the inclined.
You can slow down this downward spiral of events by taking small doses of melatonin daily. Since some people develop resistance to melatonin, you should start taking it from 4-5 nights a week (although some take it every day without experiencing any problems).
Melatonin is inexpensive and widely available supplement, which is released without a doctor’s prescription, but it can have a strong effect on our body. We advise you to use small doses if you decide to make melatonin supplements part of your anti-aged program.
For most healthy people who are not concerned about sleep problems, it is recommended to take 0.1 milligrams of melatonin half an hour before going to bed. You can increase the dose to 0.5-1.0 milligrams, which is usually not required for people without sleep problems.
If you are constantly experiencing difficulties when falling asleep, you are advised to take melatonin susceptibly for its rapid absorption. Start with 3-5 milligrams and, if necessary, increase the dose to 10 milligrams. It was experimentally proven that an increase in melatonin above the specified norm does not lead to any results. If melatonin supplements don’t help you, you should consult your doctor.
If you wake up often during the night, try to detect the time of melatonin production. Please note that you will feel tired in the morning. If you fall asleep hard or wake up often at night, try to combine foods that have both a fast-acting and slow-release formula.
In order not to experience problems when changing time zones (jetlag), you should take 3 milligrams of melatonin when going to bed in the new place for the first three days. You will have to experiment a little to find the best dose of melatonin for you.
The materials are introductory. Remember, self-medication is life-threatening, for advice on the use of any medications and treatments, consult a doctor.
So that you understand better, read my article entitled Aging Hormones and Young Hormones
